Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07FRV
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| Drug Name |
Ramipril
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| Synonyms |
ramipril; 87333-19-5; Tritace; Altace; Carasel; Triatec; Ramace; Delix; Vesdil; Acovil; Cardace; Lostapres; Quark; Hytren; Ramiprilum [Latin]; Hoe-498; Ramiprilum; Pramace; HOE 498; Altace (TN); UNII-L35JN3I7SJ; CHEMBL1168; L35JN3I7SJ; CHEBI:8774; C23H32N2O5; Ramipril
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| Drug Type |
Small molecular drug
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| Indication | Acute heart failure [ICD-11: BD10-BD13; ICD-9: 428] | Approved | [1] | |
| Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Phase 2 | [2] | ||
| Therapeutic Class |
Antiviral Agents
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| Structure |
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Download2D MOL |
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| Formula |
C23H32N2O5
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| Canonical SMILES |
CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(=O)O
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| InChI |
1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
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| InChIKey |
HDACQVRGBOVJII-JBDAPHQKSA-N
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| CAS Number |
CAS 87333-19-5
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:8774
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | HUMAN angiotensin-converting enzyme (ACE) | Target Info | Inhibitor | [3] |
| References | Top | |||
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| REF 1 | FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 202392. | |||
| REF 2 | ClinicalTrials.gov (NCT04366050) Ramipril for the Treatment of COVID-19. U.S. National Institutes of Health. | |||
| REF 3 | Outcomes in Patients with COVID-19 Infection Taking ACEI/ARB. Curr Cardiol Rep. 2020 Apr 14;22(5):31. | |||
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