Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07FHZ
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| Former ID |
DNC001219
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| Drug Name |
Ro 20-1724
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| Synonyms |
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; RO 20-1724; 29925-17-5; 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one; ro-20-1724; Ro 201724; CHEMBL18701; 4-[(3-butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one; 2-Imidazolidinone, 4-((3-butoxy-4-methoxyphenyl)methyl)-; RO-201724; 2-Imidazolidinone, 4-((3-butoxy-4-methoxyphenyl)methyl)-, (+-)-; 4-(3-butoxy-4-methoxy-benzyl)imidazolidin-2-one; 34185-37-0; 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone; SR-01000075647; keratan sulfate I; Keratan sulphate I; Naphthoquinone analogs
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| Drug Type |
Small molecular drug
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Terminated | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H22N2O3
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| Canonical SMILES |
CCCCOC1=C(C=CC(=C1)CC2CNC(=O)N2)OC
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| InChI |
1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)
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| InChIKey |
PDMUULPVBYQBBK-UHFFFAOYSA-N
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| CAS Number |
CAS 29925-17-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5146344, 7980528, 8153130, 11121423, 11121903, 11362492, 11364754, 11365054, 11367316, 11367616, 11369878, 11370255, 11370256, 11373070, 11373217, 11375778, 11378043, 11491641, 11495654, 14824380, 17404767, 24278195, 26613194, 26747110, 26751709, 26759463, 29224155, 46500386, 47216899, 47662431, 47810881, 48185112, 48259380, 48259381, 48478658, 50067170, 50070586, 50071197, 50104396, 50104397, 50104398, 50104399, 53777310, 53789843, 53800559, 57322600, 80110624, 85084418, 85230941, 85787734
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| ChEBI ID |
CHEBI:111173
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5258). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003923) | |||
| REF 3 | Role of the Cdc25A phosphatase in human breast cancer. J Clin Invest. 2000 Sep;106(6):753-61. | |||
| REF 4 | Increased interleukin-4 production by atopic mononuclear leukocytes correlates with increased cyclic adenosine monophosphate-phosphodiesterase activity and is reversible by phosphodiesterase inhibition. J Invest Dermatol. 1993 May;100(5):681-4. | |||
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