Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07EWF
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| Former ID |
DIB019264
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| Drug Name |
PMID23412139C16
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| Synonyms |
0V6; GTPL8698; BDBM50392835
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C18H17ClN4OS
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| Canonical SMILES |
CC#CC1=CC(=CN=C1)C2=CC(=C(S2)C3(CC(=O)N(C(=N3)N)C)C)Cl
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| InChI |
1S/C18H17ClN4OS/c1-4-5-11-6-12(10-21-9-11)14-7-13(19)16(25-14)18(2)8-15(24)23(3)17(20)22-18/h6-7,9-10H,8H2,1-3H3,(H2,20,22)/t18-/m0/s1
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| InChIKey |
IJYPXSRDUPWKPB-SFHVURJKSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Beta-secretase (BACE) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor that Affords Robust CNS A Reduction. ACS Med Chem Lett. 2012 Nov 8;3(11):897-902. | |||
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