Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07DTM
|
|||
| Former ID |
DIB000157
|
|||
| Drug Name |
Cetraxal Otic
|
|||
| Synonyms |
Ciprofloxacin otic
Click to Show/Hide
|
|||
| Indication | Otitis externa [ICD-11: AA00-AA13] | Phase 3 | [1], [2] | |
| Company |
Salvat Laboratories
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Haemophilus influenzae DNA gyrase A (Hae-influ gyrA) | Target Info | Modulator | [1], [2], [3] |
| Streptococcus Topoisomerase IV A (Stre-coc parC) | Target Info | Modulator | [1], [2], [3] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Chem Biol. 2010 May 28;17(5):421-33. | |||
| REF 2 | DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. | |||
| REF 3 | Selective Targeting of Topoisomerase IV and DNA Gyrase in Staphylococcus aureus: Different Patterns of Quinolone- Induced Inhibition of DNA Synthesis. Antimicrob Agents Chemother. 2000 August; 44(8):2160-2165. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.