Drug Information
Drug General Information | Top | |||
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Drug ID |
D07DJR
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Drug Name |
Pyrimidine derivative 15
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Synonyms |
PMID28621580-Compound-WO2015123722c58
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Drug Type |
Small molecular drug
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Company |
BIONOMICS LIMITED
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | Vascular endothelial growth factor receptor 3 (FLT-4) | Target Info | Inhibitor | [1] |
Target's Patent Info | Vascular endothelial growth factor receptor 3 (FLT-4) | Target's Patent Info | [1] | |
KEGG Pathway | Ras signaling pathway | |||
Rap1 signaling pathway | ||||
Cytokine-cytokine receptor interaction | ||||
PI3K-Akt signaling pathway | ||||
Focal adhesion | ||||
NetPath Pathway | TNFalpha Signaling Pathway | |||
Pathway Interaction Database | VEGF and VEGFR signaling network | |||
VEGFR3 signaling in lymphatic endothelium | ||||
Reactome | VEGF binds to VEGFR leading to receptor dimerization | |||
WikiPathways | Signaling by VEGF |
References | Top | |||
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REF 1 | VEGFR-2 inhibitors and the therapeutic applications thereof: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Sep;27(9):987-1004. |
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