Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07CQI
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| Former ID |
DNC004670
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| Drug Name |
2-Sulfamoyl-benzoic acid methyl ester
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| Synonyms |
57683-71-3; Methyl 2-(aminosulfonyl)benzoate; methyl 2-sulfamoylbenzoate; 2-Carbomethoxybenzenesulfonamide; (2-Methoxycarbonyl)benzene sulfonamide; 2-Sulfamoylbenzoic acid methyl ester; Methyl o-sulphamoylbenzoate; Benzoic acid, 2-(aminosulfonyl)-, methyl ester; EINECS 260-903-2; BENZOIC ACID, 2-SULFAMOYL-, METHYL ESTER; BRN 2728611; 2-aminosulfonyl-benzoic acid methyl ester; CHEMBL148680; CHEBI:83512; 2-methoxycarbonylphenylsulfonamide; VSOOBQALJVLTBH-UHFFFAOYSA-N; MFCD00009808; 2-(methoxycarbonyl)benzenesulphonamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H9NO4S
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| Canonical SMILES |
COC(=O)C1=CC=CC=C1S(=O)(=O)N
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| InChI |
1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12)
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| InChIKey |
VSOOBQALJVLTBH-UHFFFAOYSA-N
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| CAS Number |
CAS 57683-71-3
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:83512
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase IX (CA-IX) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
| Reactome | Regulation of gene expression by Hypoxia-inducible Factor | |||
| Reversible hydration of carbon dioxide | ||||
| Erythrocytes take up carbon dioxide and release oxygen | ||||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| WikiPathways | Vitamin D Receptor Pathway | |||
| Reversible Hydration of Carbon Dioxide | ||||
| Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | ||||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/membrane-associated carbonic anhydrase isozymes I, II, and IX with sulfonamide... J Med Chem. 2005 Mar 24;48(6):2121-5. | |||
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