Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07ANO
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| Former ID |
DIB012204
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| Drug Name |
Synthetic neutrophil inhibitor peptide
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| Synonyms |
SNIP; Nalpha-Acetyl-L-arginyl-L-glutamyl-glycyl-L-seryl-L-tyrosyl-L-phenylalanyl-L-phenylalanyl-glycyl-L-aspartyl-L-asparaginyl-L-alaninamide
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| Drug Type |
Small molecular drug
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| Indication | Rhinitis [ICD-11: FA20; ICD-10: J31.0] | Phase 1 | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C9H10ClN2O5PS
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| Canonical SMILES |
COP(=O)(OC)SCN1C2=C(C=C(C=N2)Cl)OC1=O
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| InChI |
1S/C9H10ClN2O5PS/c1-15-18(14,16-2)19-5-12-8-7(17-9(12)13)3-6(10)4-11-8/h3-4H,5H2,1-2H3
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| InChIKey |
VNKBTWQZTQIWDV-UHFFFAOYSA-N
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| CAS Number |
CAS 35575-96-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
6756098, 8194647, 14951110, 24775819, 24868788, 26757342, 43127798, 48425768, 50009468, 50111607, 50394980, 51091804, 53790572, 57318223, 57650291, 70503779, 91696359, 103847738, 104350562, 117627579, 124489376, 124892666, 125501339, 134411593, 135029482, 137248607, 143500464, 144211326, 152134199, 152247683, 160687967, 162177736, 162252613, 164175165, 164788089, 164836021, 176317894, 179322572, 184545210, 187072614, 198971204, 223516196, 226414696, 241064842, 249979745
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| ChEBI ID |
CHEBI:38578
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | PMN apoptosis and chemotaxis (PMNAC) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Attenuation of interleukin 8-induced nasal inflammation by an inhibitor peptide. Am J Respir Crit Care Med. 2001 Apr;163(5):1198-205. | |||
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