Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06YPU
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| Former ID |
DIB008368
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| Drug Name |
Dexibuprofen
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| Synonyms |
(S)-(+)-Ibuprofen; 51146-56-6; DEXIBUPROFEN; S(+)-Ibuprofen; (S)-2-(4-Isobutylphenyl)propanoic acid; (S)-Ibuprofen; d-Ibuproten; (S)-(+)-2-(4-Isobutylphenyl)propionic acid; (+)-(S)-p-Isobutylhydratropic acid; Seractil; (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid; (S)-(+)-4-Isobutyl-alpha-methylphenylacetic acid; UNII-671DKG7P5S; S-(+)-ibuprofen; (2S)-2-(4-isobutylphenyl)propanoic acid; CHEMBL175; 671DKG7P5S; CHEBI:43415; (S)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid; NCGC00016861-05
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| Drug Type |
Small molecular drug
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| Indication | Ankylosing spondylitis [ICD-11: FA92.0; ICD-10: M45; ICD-9: 720] | Approved | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C13H18O2
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| Canonical SMILES |
CC(C)CC1=CC=C(C=C1)C(C)C(=O)O
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| InChI |
1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m0/s1
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| InChIKey |
HEFNNWSXXWATRW-JTQLQIEISA-N
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| CAS Number |
CAS 51146-56-6
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:43415
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase (COX) | Target Info | Modulator | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Comparison of the efficacy and tolerability of dexibuprofen and celecoxib in the treatment of osteoarthritis of the hip. Int J Clin Pharmacol Ther. 2003 Apr;41(4):153-64. | |||
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