Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06XTA
|
|||
| Drug Name |
PMID27998201-Compound-17
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Hair loss [ICD-11: ED70] | Patented | [1] | |
| Company |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA DIAMOND, Scott, L. BEAVERS, Mary, Pat HURYN, Donna MYERS, Michael, C. SMITH, Amos, B. SHAH, Parag, P. LIU, Zhuqin
|
|||
| Structure |
 |
Download2D MOL |
||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin B (CTSB) | Target Info | Inhibitor | [1] |
| Cathepsin L (CTSL) | Target Info | Inhibitor | [1] | |
| Cathepsin S (CTSS) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Cathepsin B (CTSB) | Target's Patent Info | [1] | |
| Cathepsin L (CTSL) | Target's Patent Info | [1] | ||
| Cathepsin S (CTSS) | Target's Patent Info | [1] | ||
| KEGG Pathway | Lysosome | |||
| Phagosome | ||||
| Antigen processing and presentation | ||||
| Proteoglycans in cancer | ||||
| Rheumatoid arthritis | ||||
| Tuberculosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| TCR Signaling Pathway | ||||
| IL2 Signaling Pathway | ||||
| Leptin Signaling Pathway | ||||
| Reactome | Endosomal/Vacuolar pathway | |||
| Collagen degradation | ||||
| Degradation of the extracellular matrix | ||||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | |||
| Class I MHC mediated antigen processing & presentation | ||||
| Trafficking and processing of endosomal TLR | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.