Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06XLC
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| Former ID |
DIB006944
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| Drug Name |
BMS-739562
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| Synonyms |
Pyrrolo triazine-based aurora kinase inhibitors (cancer); Pyrrolo triazine-based aurora kinase inhibitors (cancer), Bristol-Myers Squibb
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
| Company |
Bristol-Myers Squibb Co
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aurora kinase C (AURKC) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Oocyte meiosis | |||
| Reactome | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | |||
| Separation of Sister Chromatids | ||||
| Resolution of Sister Chromatid Cohesion | ||||
| RHO GTPases Activate Formins | ||||
| WikiPathways | EGF/EGFR Signaling Pathway | |||
| JAK/STAT | ||||
| Gastric Cancer Network 1 | ||||
| Integrated Breast Cancer Pathway | ||||
| APC/C-mediated degradation of cell cycle proteins | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1936). | |||
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