Drug Information
Drug General Information | Top | |||
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Drug ID |
D06WPM
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Former ID |
DIB004329
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Drug Name |
Coprexa
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Synonyms |
Tetrathiomolybdate
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Drug Type |
Small molecular drug
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Indication | Neurological disorder [ICD-11: 6B60] | Phase 3 | [1] | |
Company |
Pipex Pharmaceuticals
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Structure |
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Download2D MOL |
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Formula |
H2MoS4-2
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Canonical SMILES |
[SH-].[SH-].S=[Mo]=S
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InChI |
1S/Mo.2H2S.2S/h;2*1H2;;/p-2
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InChIKey |
VVRHUOPINLMZBL-UHFFFAOYSA-L
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CAS Number |
CAS 16330-92-0
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PubChem Compound ID | ||||
PubChem Substance ID | ||||
ChEBI ID |
CHEBI:30703
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Target and Pathway | Top | |||
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Target(s) | Superoxide dismutase Cu-Zn (SOD Cu-Zn) | Target Info | Inhibitor | [1] |
BioCyc | Reactive oxygen species degradation | |||
KEGG Pathway | Peroxisome | |||
Amyotrophic lateral sclerosis (ALS) | ||||
Huntington's disease | ||||
Prion diseases | ||||
NetPath Pathway | TCR Signaling Pathway | |||
Pathwhiz Pathway | Degradation of Superoxides | |||
Pathway Interaction Database | Validated nuclear estrogen receptor alpha network | |||
FOXA1 transcription factor network | ||||
Reactome | Platelet degranulation | |||
Detoxification of Reactive Oxygen Species | ||||
WikiPathways | Oxidative Stress | |||
Copper homeostasis | ||||
Detoxification of Reactive Oxygen Species | ||||
Nifedipine Activity | ||||
Amyotrophic lateral sclerosis (ALS) | ||||
Dopamine metabolism | ||||
AGE/RAGE pathway | ||||
Folate Metabolism | ||||
Vitamin B12 Metabolism | ||||
Selenium Micronutrient Network |
References | Top | |||
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REF 1 | Copper binding by tetrathiomolybdate attenuates angiogenesis and tumor cell proliferation through the inhibition of superoxide dismutase 1. Clin Cancer Res. 2006 Aug 15;12(16):4974-82. |
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