Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D06TSI
|
|||
Former ID |
DNC009254
|
|||
Drug Name |
2,7-Bis[3-(propylamino)propionamido]anthraquinone
|
|||
Synonyms |
2,7-Bis[3-(propylamino)propionamido]anthraquinone; SCHEMBL4298186; CHEMBL481160
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C26H32N4O4
|
|||
Canonical SMILES |
CCCNCCC(=O)NC1=CC2=C(C=C1)C(=O)C3=C(C2=O)C=C(C=C3)NC(=O)CCNCCC
|
|||
InChI |
1S/C26H32N4O4/c1-3-11-27-13-9-23(31)29-17-5-7-19-21(15-17)26(34)22-16-18(6-8-20(22)25(19)33)30-24(32)10-14-28-12-4-2/h5-8,15-16,27-28H,3-4,9-14H2,1-2H3,(H,29,31)(H,30,32)
|
|||
InChIKey |
JELVSCOBEUHNBV-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
KEGG Pathway | HTLV-I infection | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
Regulation of Telomerase | ||||
IL2 signaling events mediated by PI3K | ||||
Regulation of nuclear beta catenin signaling and target gene transcription | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
WikiPathways | TGF beta Signaling Pathway | |||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Telomere Maintenance |
References | Top | |||
---|---|---|---|---|
REF 1 | Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. Bioorg Med Chem. 2008 Jul 15;16(14):6976-86. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.