Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06SCF
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| Former ID |
DNC002678
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| Drug Name |
Biliverdine Ix Alpha
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| Synonyms |
biliverdine; UNII-O9MIA842K9; NSC 62793; O9MIA842K9; CHEBI:17033; Biliverdin IX; 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbilin-1(19)(21H,24H)-dione; Biliverdine dihydrochloride; QBUVFDKTZJNUPP-BBROENKCSA-N; Protobiliverdin IX; EINECS 204-042-2
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C33H34N4O6
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| Canonical SMILES |
CC1=C(C(=CC2=C(C(=C(N2)C=C3C(=C(C(=O)N3)C)C=C)C)CCC(=O)O)NC1=CC4=NC(=O)C(=C4C)C=C)CCC(=O)O
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| InChI |
1S/C33H34N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-15,34-35H,1-2,9-12H2,3-6H3,(H,37,42)(H,38,39)(H,40,41)/b24-13-,27-14-,28-15-
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| InChIKey |
RCNSAJSGRJSBKK-NSQVQWHSSA-N
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| CAS Number |
CAS 114-25-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:17033
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Heme oxygenase 1 (HMOX1) | Target Info | Inhibitor | [1] |
| BioCyc | Heme degradation | |||
| KEGG Pathway | Porphyrin and chlorophyll metabolism | |||
| HIF-1 signaling pathway | ||||
| Mineral absorption | ||||
| MicroRNAs in cancer | ||||
| Pathwhiz Pathway | Porphyrin Metabolism | |||
| Pathway Interaction Database | Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||
| HIF-1-alpha transcription factor network | ||||
| Reactome | Iron uptake and transport | |||
| WikiPathways | Oxidative Stress | |||
| Transcriptional activation by NRF2 | ||||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| miR-targeted genes in squamous cell - TarBase | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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