Drug Information
Drug General Information | Top | |||
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Drug ID |
D06RQV
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Former ID |
DNC006461
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Drug Name |
2-methyl-3-(pyridin-4-yl)-1H-indol-6-amine
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Synonyms |
CHEMBL207502; 2-methyl-3-(pyridin-4-yl)-1H-indol-6-amine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H13N3
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Canonical SMILES |
CC1=C(C2=C(N1)C=C(C=C2)N)C3=CC=NC=C3
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InChI |
1S/C14H13N3/c1-9-14(10-4-6-16-7-5-10)12-3-2-11(15)8-13(12)17-9/h2-8,17H,15H2,1H3
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InChIKey |
AAIHLDQORIUJKB-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) | Target Info | Inhibitor | [1] |
BioCyc | Purine nucleotides degradation | |||
Urate biosynthesis/inosine 5'-phosphate degradation | ||||
Guanosine nucleotides de novo biosynthesis | ||||
Superpathway of purine nucleotide salvage | ||||
Purine nucleotides de novo biosynthesis | ||||
Guanosine ribonucleotides de novo biosynthesis | ||||
KEGG Pathway | Purine metabolism | |||
Drug metabolism - other enzymes | ||||
Metabolic pathways | ||||
Panther Pathway | De novo purine biosynthesis | |||
Reactome | Purine ribonucleoside monophosphate biosynthesis |
References | Top | |||
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REF 1 | Low molecular weight indole fragments as IMPDH inhibitors. Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. |
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