Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06QOX
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| Former ID |
DNC011514
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| Drug Name |
1,3-Diphenyl-1H-chromeno[4,3-c]pyrazol-4-one
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| Synonyms |
100008-84-2; [1]Benzopyrano[4,3-c]pyrazol-4(1H)-one, 1,3-diphenyl-; ACMC-20m32m; CHEMBL99633; CTK0G9179; DTXSID70541117; AKOS030534409; J3.620.041C; 1,3-Diphenyl[1]benzopyrano[4,3-c]pyrazole-4(1H)-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H14N2O2
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| Canonical SMILES |
C1=CC=C(C=C1)C2=NN(C3=C2C(=O)OC4=CC=CC=C43)C5=CC=CC=C5
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| InChI |
1S/C22H14N2O2/c25-22-19-20(15-9-3-1-4-10-15)23-24(16-11-5-2-6-12-16)21(19)17-13-7-8-14-18(17)26-22/h1-14H
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| InChIKey |
ZPXTZMAWXDLUOO-UHFFFAOYSA-N
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| CAS Number |
CAS 100008-84-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, binding studies, and structure-activity relationships of 1-aryl-and 2-aryl[1]benzopyranopyrazol-4-ones, central benzodiazepine receptor ... J Med Chem. 1988 Jan;31(1):1-3. | |||
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