Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06QOJ
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| Former ID |
DIB017034
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| Drug Name |
RS-8359
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| Synonyms |
CS-8359; TUK-9261; TUK-9262; TUK-9508
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| Drug Type |
Small molecular drug
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| Indication | Major depressive disorder [ICD-11: 6A70.3; ICD-10: F32.2] | Discontinued in Phase 2 | [1] | |
| Company |
Sankyo Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C14H12N4O
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| Canonical SMILES |
C1CC2=C(C1O)N=CN=C2NC3=CC=C(C=C3)C#N
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| InChI |
1S/C14H12N4O/c15-7-9-1-3-10(4-2-9)18-14-11-5-6-12(19)13(11)16-8-17-14/h1-4,8,12,19H,5-6H2,(H,16,17,18)
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| InChIKey |
YKTSVZRWKHWINV-UHFFFAOYSA-N
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| CAS Number |
CAS 105365-76-2
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000633) | |||
| REF 2 | Stereospecific oxidation of the (S)-enantiomer of RS-8359, a selective and reversible monoamine oxidase A (MAO-A) inhibitor, by aldehyde oxidase. Xenobiotica. 2005 Jun;35(6):561-73. | |||
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