Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06PHH
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| Former ID |
DIB007628
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| Drug Name |
Rimacalib
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| Synonyms |
SMP-114
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| Drug Type |
Small molecular drug
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| Indication | Rheumatoid arthritis [ICD-11: FA20] | Phase 2 | [1] | |
| Company |
Sumitomo Pharmaceuticals Co Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H23FN4O2
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| Canonical SMILES |
CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C3=NOC(=C3)N=C(N)N4CCOCC4
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| InChI |
1S/C22H23FN4O2/c1-15(17-7-8-18(19(23)13-17)16-5-3-2-4-6-16)20-14-21(29-26-20)25-22(24)27-9-11-28-12-10-27/h2-8,13-15H,9-12H2,1H3,(H2,24,25)/t15-/m0/s1
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| InChIKey |
MYTIJGWONQOOLC-HNNXBMFYSA-N
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| CAS Number |
CAS 215174-50-8
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | CaMKII inhibitors: from research tools to therapeutic agents. Front Pharmacol. 2014; 5: 21. | |||
| REF 2 | Role for CaMKII inhibition in rheumatoid arthritis: effects on HIF-1-induced VEGF production by rheumatoid synovial fibroblasts. Ann N Y Acad Sci. 2009 Sep;1173:706-11. | |||
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