Drug Information
Drug General Information | Top | |||
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Drug ID |
D06OLJ
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Former ID |
DNC010861
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Drug Name |
AMG-7160
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Synonyms |
AMG-7160; CHEMBL1086588; 4-Bromo-N-[2,2,2-trichloro-1-(4-chloro-phenylsulfanyl)-ethyl]-benzamide; 4-bromo-N-{2,2,2-trichloro-1-[(4-chlorophenyl)sulfanyl]ethyl}benzamide; 4-bromo-n-(2,2,2-trichloro-1-((4-chlorophenyl)sulfanyl)ethyl)benzamide; BAS 00084574; AC1MJD0X; SCHEMBL19743234; MolPort-001-818-003; BDBM50318458; AKOS016369423; AKOS000619708; MCULE-2387805859; ST082345; AG-690/32533021; 4-bromo-N-(2,2,2-trichloro-1-(4-chlorophenylthio)ethyl)benzamide; 4-bromo-N-[2,2,2-trichloro-1-(4-chlorophenyl)sulfanylethyl]benzamide
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C15H10BrCl4NOS
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Canonical SMILES |
C1=CC(=CC=C1C(=O)NC(C(Cl)(Cl)Cl)SC2=CC=C(C=C2)Cl)Br
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InChI |
1S/C15H10BrCl4NOS/c16-10-3-1-9(2-4-10)13(22)21-14(15(18,19)20)23-12-7-5-11(17)6-8-12/h1-8,14H,(H,21,22)
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InChIKey |
APLQHKFABMHWHP-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Transformation-sensitive protein p120 (TRPA1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Inflammatory mediator regulation of TRP channels | |||
Reactome | TRP channels |
References | Top | |||
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REF 1 | Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. J Med Chem. 2010 Jul 22;53(14):5085-107. |
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