Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06MZB
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| Former ID |
DNC009302
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| Drug Name |
KNI-10081
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| Synonyms |
KNI-10081; CHEMBL508116; BDBM50273721
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C34H39N3O6S
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| Canonical SMILES |
CC1=CC=C(C=C1)OCC(=O)NC(CC2=CC=CC=C2)C(C(=O)N3CSC(C3C(=O)NC4C(CC5=CC=CC=C45)O)(C)C)O
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| InChI |
1S/C34H39N3O6S/c1-21-13-15-24(16-14-21)43-19-28(39)35-26(17-22-9-5-4-6-10-22)30(40)33(42)37-20-44-34(2,3)31(37)32(41)36-29-25-12-8-7-11-23(25)18-27(29)38/h4-16,26-27,29-31,38,40H,17-20H2,1-3H3,(H,35,39)(H,36,41)/t26-,27+,29-,30-,31+/m0/s1
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| InChIKey |
CJVKWQTVDIZBSG-VFCPCCRCSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Plasmepsin 2 (Malaria PLA2) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin. Bioorg Med Chem. 2008 Dec 1;16(23):10049-60. | |||
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