Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06MNV
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| Former ID |
DNC013565
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| Drug Name |
1-(1-phenylethylidene)thiosemicarbazide
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| Synonyms |
CHEMBL256868; Acetophenone thiosemicarbazone; AC1NSE5V; SCHEMBL17666972; MolPort-000-248-706; ACETOPHENONE-THIOSEMICARBAZONE; BDBM50376200; ZINC13655939; AKOS002388568; AKOS002238721; [(Z)-1-phenylethylideneamino]thiourea; [(Z)-(1-phenylethylidene)amino]thiourea; KB-106912; ST50101590; (z)-2-(1-phenylethylidene)hydrazinecarbothioamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H11N3S
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| Canonical SMILES |
CC(=NNC(=S)N)C1=CC=CC=C1
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| InChI |
1S/C9H11N3S/c1-7(11-12-9(10)13)8-5-3-2-4-6-8/h2-6H,1H3,(H3,10,12,13)/b11-7-
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| InChIKey |
JMULZUQMMLAALR-XFFZJAGNSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors. Bioorg Med Chem. 2008 Feb 1;16(3):1096-102. | |||
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