Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06LNW
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| Former ID |
DNAP001279
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| Drug Name |
Fidaxomicin
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| Synonyms |
Dificid (TN)
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| Drug Type |
Small molecular drug
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| Indication | Clostridium difficile associated diarrhea [ICD-11: 1A04; ICD-10: A04.7] | Approved | [1] | |
| Company |
Astellas
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| Structure |
 |
Download2D MOL |
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| Formula |
C52H74Cl2O18
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| Canonical SMILES |
CCC1C=C(C(CC=CC=C(C(=O)OC(CC=C(C=C(C1OC2C(C(C(C(O2)(C)C)OC(=O)C(C)C)O)O)C)C)C(C)O)COC3C(C(C(C(O3)C)OC(=O)C4=C(C(=C(C(=C4O)Cl)O)Cl)CC)O)OC)O)C
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| InChI |
1S/C52H74Cl2O18/c1-13-30-22-26(6)33(56)18-16-15-17-31(23-66-51-45(65-12)42(61)44(29(9)67-51)69-49(64)35-32(14-2)36(53)39(58)37(54)38(35)57)48(63)68-34(28(8)55)20-19-25(5)21-27(7)43(30)70-50-41(60)40(59)46(52(10,11)72-50)71-47(62)24(3)4/h15-17,19,21-22,24,28-30,33-34,40-46,50-51,55-61H,13-14,18,20,23H2,1-12H3/b16-15+,25-19+,26-22+,27-21+,31-17+/t28-,29-,30+,33+,34+,40-,41+,42+,43+,44-,45+,46+,50-,51-/m1/s1
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| InChIKey |
ZVGNESXIJDCBKN-UUEYKCAUSA-N
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| CAS Number |
CAS 873857-62-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ADReCS Drug ID | BADD_D00896 | |||
| SuperDrug ATC ID |
A07AA12
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial RNA polymerase switch region (Bact RNAP-SR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91-4. | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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