Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06KTD
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| Former ID |
DNC004671
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| Drug Name |
2-Hydrazinocarbonyl-benzenesulfonamide
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| Synonyms |
102169-52-8; 2-(hydrazinecarbonyl)benzenesulfonamide; 2-(hydrazinocarbonyl)benzenesulfonamide; 2-Hydrazinocarbonyl-benzenesulfonamide; 2-(hydrazinecarbonyl)benzene-1-sulfonamide; Benzoic acid,2-(aminosulfonyl)-, hydrazide; hydrazide deriv. 6; AC1M8OJR; ACMC-1BW2D; AC1Q54UM; Oprea1_607731; CHEMBL361191; CTK4A0755; BDBM12153; DTXSID30368807; HMS1788K01; ZX-AN012798; ZINC3372954; ALBB-014056; 7604AC; STL301522; AKOS000116142; FCH1317207; MCULE-6758898279; 2-(hydrazinylcarbonyl)benzenesulfonamide; BBV-40193034; Benzoic acid, 2-(aminosul
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C7H9N3O3S
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| Canonical SMILES |
C1=CC=C(C(=C1)C(=O)NN)S(=O)(=O)N
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| InChI |
1S/C7H9N3O3S/c8-10-7(11)5-3-1-2-4-6(5)14(9,12)13/h1-4H,8H2,(H,10,11)(H2,9,12,13)
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| InChIKey |
YWPOXIABDFDDSR-UHFFFAOYSA-N
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| CAS Number |
CAS 102169-52-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase IX (CA-IX) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| Regulation of gene expression by Hypoxia-inducible Factor | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| Vitamin D Receptor Pathway | ||||
| Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/membrane-associated carbonic anhydrase isozymes I, II, and IX with sulfonamide... J Med Chem. 2005 Mar 24;48(6):2121-5. | |||
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