Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06KMO
|
|||
| Former ID |
DNC000352
|
|||
| Drug Name |
Brocresine
|
|||
| Synonyms |
Brocresine; Brocresin; 555-65-7; 3-(Aminooxymethyl)-6-bromphenol; Brocresinum [INN-Latin]; Brocresina [INN-Spanish]; NSD 1055; Brocresine [USAN:INN:BAN]; UNII-11F6O06WN0; CL 54998; NSD-1055; alpha-(Aminooxy)-6-bromo-m-cresol; C7H8BrNO2; 5-((Aminooxy)methyl)-2-bromophenol; O-)4-Brom-3-hydroxybenzyl)hydroxylamin; BRN 1945736; Phenol, 5-((aminooxy)methyl)-2-bromo-; 4-Bromo-3-hydroxybenzyloxyamine; QNWOSJAGFSUDFE-UHFFFAOYSA-N; 11F6O06WN0; 5-[(Aminooxy)methyl]-2-bromophenol; m-CRESOL, alpha-(AMINOOXY)-6-BROMO-; Brocresina
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C7H8BrNO2
|
|||
| Canonical SMILES |
C1=CC(=C(C=C1CON)O)Br
|
|||
| InChI |
1S/C7H8BrNO2/c8-6-2-1-5(4-11-9)3-7(6)10/h1-3,10H,4,9H2
|
|||
| InChIKey |
QNWOSJAGFSUDFE-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 555-65-7
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histidine decarboxylase (HDC) | Target Info | Inhibitor | [1], [2] |
| KEGG Pathway | Histidine metabolism | |||
| Metabolic pathways | ||||
| Panther Pathway | Histamine synthesis | |||
| CCKR signaling map ST | ||||
| Pathwhiz Pathway | Histidine Metabolism | |||
| WikiPathways | Biogenic Amine Synthesis | |||
| Metabolism of amino acids and derivatives | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Histamine in brain--its role in regulation of seizure susceptibility. Epilepsy Res. 1991 Nov-Dec;10(2-3):111-8. | |||
| REF 2 | Effects of brocresine (NSD-1055) and cycloheximide on amino acid decarboxylase activities in gastric mucosa of normal and vagally denervated rats. Br J Pharmacol. 1972 Dec;46(4):688-95. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.