Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06JBV
|
|||
| Former ID |
DIB005450
|
|||
| Drug Name |
SGN LIV1A
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Breast cancer [ICD-11: 2C60-2C65] | Phase 1 | [1] | |
| Company |
Seattle genetics
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Solute carrier family 39 member 6 (SLC39A6) | Target Info | . | [2] |
| WikiPathways | NRF2 pathway | |||
| Nuclear Receptors Meta-Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01969643) A Safety Study of SGN-LIV1A in Breast Cancer Patients. U.S. National Institutes of Health. | |||
| REF 2 | SGN-LIV1A: a novel antibody-drug conjugate targeting LIV-1 for the treatment of metastatic breast cancer. Mol Cancer Ther. 2014 Dec;13(12):2991-3000. | |||
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