Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06IEX
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| Former ID |
DIB006931
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| Drug Name |
Cardiotrophin-1
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| Synonyms |
Cardiotrophin-1 (acute liver failure/obesity/interferon stimulator)
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| Indication | Acute liver failure [ICD-11: DB91] | Phase 1 | [1], [2] | |
| Company |
Digna Biotech SL
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cardiotrophin-1 (CTF1) | Target Info | Stimulator | [3] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Jak-STAT signaling pathway | ||||
| WikiPathways | MicroRNAs in cardiomyocyte hypertrophy | |||
| Physiological and Pathological Hypertrophy of the Heart | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4906). | |||
| REF 2 | ClinicalTrials.gov (NCT01334697) Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of Cardiotrophin-1 in Healthy Volunteers. U.S. National Institutes of Health. | |||
| REF 3 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
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