Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06HMN
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| Drug Name |
BAY1251152
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| Synonyms |
YZCUMZWULWOUMD-UHFFFAOYSA-N; SCHEMBL15720569; (rac)-5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine; 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine
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| Indication | Haematological malignancy [ICD-11: 2B33.Y] | Phase 1 | [1] | |
| Company |
Bayer Pharmaceuticals Whippany, NJ
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| Structure |
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Download2D MOL |
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| Formula |
C19H18F2N4O2S
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| Canonical SMILES |
COC1=C(C=CC(=C1)F)C2=CC(=NC=C2F)NC3=NC=CC(=C3)CS(=N)(=O)C
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| InChI |
1S/C19H18F2N4O2S/c1-27-17-8-13(20)3-4-14(17)15-9-19(24-10-16(15)21)25-18-7-12(5-6-23-18)11-28(2,22)26/h3-10,22H,11H2,1-2H3,(H,23,24,25)
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| InChIKey |
YZCUMZWULWOUMD-UHFFFAOYSA-N
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| CAS Number |
CAS 1610358-59-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Positive transcription elongation factor b (P-TEFb) | Target Info | Inhibitor | [1] |
| KEGG Pathway | HIF-1 signaling pathway | |||
| Ubiquitin mediated proteolysis | ||||
| Pathways in cancer | ||||
| Renal cell carcinoma | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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