Drug Information
Drug General Information | Top | |||
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Drug ID |
D06FPF
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Former ID |
DIB015064
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Drug Name |
Valortim
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Synonyms |
Anthrax antibody, Medarex; MDX-1303; Anthrax antibody, Medarex/PharmAthene; Anti-B anthracis, Bristol Myers Squibb/PharmAthene; Anti-B anthracis PA (anthrax), Medarex/BMS/PharmAthene
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Drug Type |
Antibody
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Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Phase 1 | [1] | |
Company |
Pharmathene
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Target and Pathway | Top | |||
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Target(s) | Bacterial Protective antigen (Bact pagA) | Target Info | . | [2] |
Pathway Interaction Database | Cellular roles of Anthrax toxin | |||
Reactome | Uptake and function of anthrax toxins |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01265745) Dose Escalation Study of Valortim (MDX-1303) Administered Intravenously (IV) in Healthy, Normal Subjects. U.S. National Institutes of Health. | |||
REF 2 | Phase I Study Evaluating the Safety and Pharmacokinetics of MDX-1303, a Fully Human Monoclonal Antibody against Bacillus anthracis Protective Antigen, in Healthy Volunteers. Clin Vaccine Immunol. 2011 December; 18(12): 2136-2142. |
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