Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06DRH
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| Drug Name |
US9216972, 61
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| Synonyms |
SCHEMBL1806497; CHEMBL3908750; BDBM197666; US9216972, 61
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C25H18F3N3O5
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| Canonical SMILES |
C1C(CN1CC2=CC3=C(C=C2)C4=NOC(=C4CO3)C5=C(C(=NO5)C6=CC=CC=C6)C(F)(F)F)C(=O)O
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| InChI |
1S/C25H18F3N3O5/c26-25(27,28)19-20(14-4-2-1-3-5-14)29-36-23(19)22-17-12-34-18-8-13(6-7-16(18)21(17)30-35-22)9-31-10-15(11-31)24(32)33/h1-8,15H,9-12H2,(H,32,33)
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| InChIKey |
QUYMGOJIHUGBPQ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target's Patent Info | [1] | |
| KEGG Pathway | Sphingolipid signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | S1P3 pathway | |||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| Reactome | G alpha (i) signalling events | |||
| Lysosphingolipid and LPA receptors | ||||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tricyclic heterocyclic compounds. US9216972. | |||
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