Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06BNI
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| Former ID |
DNC011512
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| Drug Name |
(9H-beta-Carbolin-3-yl)-methanol
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| Synonyms |
3-hydroxymethyl-beta-carboline; 65474-79-5; UNII-00QJ5EQT3E; 9H-pyrido[3,4-b]indol-3-ylmethanol; 00QJ5EQT3E; 3-HMC; 3-(hydroxymethyl)-beta-carboline; 3-HYDROXYMETHYL-b-CARBOLINE; 9H-Pyrido[3,4-b]indole-3-methanol; 9H-pyrido(3,4-b)indole-3-methanol; Prestwick_970; Biomol-NT_000286; AC1NS42Q; DivK1c_000628; 9H-beta-carboline-3-methanol; CHEMBL417982; SCHEMBL2216848; BPBio1_001234; KBio1_000628; CTK2F5969; HMS501P10; DTXSID20215795; MolPort-005-942-230; CPBYHTDUBNSBQM-UHFFFAOYSA-N; CHEBI:114188; NINDS_000628; ZINC11535632
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C12H10N2O
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| Canonical SMILES |
C1=CC=C2C(=C1)C3=C(N2)C=NC(=C3)CO
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| InChI |
1S/C12H10N2O/c15-7-8-5-10-9-3-1-2-4-11(9)14-12(10)6-13-8/h1-6,14-15H,7H2
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| InChIKey |
CPBYHTDUBNSBQM-UHFFFAOYSA-N
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| CAS Number |
CAS 65474-79-5
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:114188
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists. J Med Chem. 1987 Apr;30(4):750-3. | |||
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