Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05ZIS
|
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| Former ID |
DIB016691
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| Drug Name |
SM-04690
|
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| Indication | Osteoarthritis [ICD-11: FA00-FA05; ICD-9: 715] | Phase 2 | [1] | |
| Company |
Samumed
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| Structure |
 |
Download2D MOL |
||
| Formula |
C29H24FN7O
|
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| Canonical SMILES |
CC(C)CC(=O)NC1=CN=CC(=C1)C2=CC3=C(C=C2)NN=C3C4=NC5=C(N4)C=NC=C5C6=CC(=CC=C6)F
|
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| InChI |
1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28(37-36-24)29-34-25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)
|
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| InChIKey |
AQDWDWAYVBQMAM-UHFFFAOYSA-N
|
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| CAS Number |
CAS 1467093-03-3
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Wnt signaling pathway (Wnt pathway) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02536833) A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects. | |||
| REF 2 | Clinical pipeline report, company report or official report of Phrma.org Arthritis 2014. | |||
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