Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05XZQ
|
|||
| Former ID |
DIB007396
|
|||
| Drug Name |
HepaStem
|
|||
| Indication | Liver failure [ICD-11: DB99.7] | Phase 2 | [1] | |
| Company |
Promethera Biosciences SA/NV
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phenylalanine hydroxylase (PAH) | Target Info | Modulator | [2] |
| BioCyc | Phenylalanine degradation/tyrosine biosynthesis | |||
| KEGG Pathway | Phenylalanine metabolism | |||
| Phenylalanine, tyrosine and tryptophan biosynthesis | ||||
| Metabolic pathways | ||||
| Biosynthesis of amino acids | ||||
| Pathwhiz Pathway | Phenylalanine and Tyrosine Metabolism | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Biogenic Amine Synthesis | ||||
| Metabolism of amino acids and derivatives | ||||
| Abnormal metabolism in phenylketonuria | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02489292) Study to Evaluate the Efficacy of HepaStem in Urea Cycle Disorders Paediatric Patients (HEP002). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1240). | |||
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