Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05WGA
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| Former ID |
DNC007408
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| Drug Name |
2-(4-methoxyphenyl)-N-(thiazol-2-yl)acetamide
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| Synonyms |
2-(4-methoxyphenyl)-N-(1,3-thiazol-2-yl)acetamide; AC1LGGXP; Cambridge id 5286247; Oprea1_702537; Oprea1_294245; CHEMBL227898; MolPort-001-026-371; ZINC253385; STL503574; AKOS000673322; MCULE-3731631352; BAS 00626097; KB-115460; ST50912475; 2-(4-Methoxy-phenyl)-N-thiazol-2-yl-acetamide; 2-(4-methoxyphenyl)-N-1,3-thiazol-2-ylacetamide; Z28173731
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H12N2O2S
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| Canonical SMILES |
COC1=CC=C(C=C1)CC(=O)NC2=NC=CS2
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| InChI |
1S/C12H12N2O2S/c1-16-10-4-2-9(3-5-10)8-11(15)14-12-13-6-7-17-12/h2-7H,8H2,1H3,(H,13,14,15)
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| InChIKey |
SPAPWVUPZKTBMH-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | LOX-5 messenger RNA (ALOX5 mRNA) | Target Info | Inhibitor | [1] |
| BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Lipoxin biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening. J Med Chem. 2007 May 31;50(11):2640-6. | |||
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