Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05VWZ
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| Former ID |
DNC006518
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| Drug Name |
2-(3-carboxybenzyl)succinic acid
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| Synonyms |
2-(3-carboxybenzyl)succinic acid; carboxylate, 39; 2-[(3-carboxyphenyl)methyl]butanedioic Acid; Butanedioic acid, 2-[(3-carboxyphenyl)methyl]-; CHEMBL209190; BDBM17782
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H12O6
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| Canonical SMILES |
C1=CC(=CC(=C1)C(=O)O)CC(CC(=O)O)C(=O)O
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| InChI |
1S/C12H12O6/c13-10(14)6-9(12(17)18)5-7-2-1-3-8(4-7)11(15)16/h1-4,9H,5-6H2,(H,13,14)(H,15,16)(H,17,18)
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| InChIKey |
WCLWDNBZTFVGIR-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Metabolic pathways | ||||
| Vitamin digestion and absorption | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Reactome | Amino acid synthesis and interconversion (transamination) | |||
| WikiPathways | One Carbon Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structural optimization of thiol-based inhibitors of glutamate carboxypeptidase II by modification of the P1' side chain. J Med Chem. 2006 May 18;49(10):2876-85. | |||
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