Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05VLN
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| Former ID |
DIB004476
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| Drug Name |
Isomazole
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| Synonyms |
Isosulmazole; Isomazole fumarate; Isomazole hydrochloride; EMD-41064; EMD-47200; EMD-50250; EMD-52750; LY-175326
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| Drug Type |
Small molecular drug
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Terminated | [1] | |
| Company |
Merck KGaA
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| Structure |
 |
Download2D MOL |
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| Formula |
C14H13N3O2S
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| Canonical SMILES |
COC1=C(C=CC(=C1)S(=O)C)C2=NC3=C(N2)C=NC=C3
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| InChI |
1S/C14H13N3O2S/c1-19-13-7-9(20(2)18)3-4-10(13)14-16-11-5-6-15-8-12(11)17-14/h3-8H,1-2H3,(H,16,17)
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| InChIKey |
JQUKCPUPFALELS-UHFFFAOYSA-N
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| CAS Number |
CAS 86315-52-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:91691
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase (PDE) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000373) | |||
| REF 2 | Effects of isomazole on force of contraction and phosphodiesterase isoenzymes I-IV in nonfailing and failing human hearts. J Cardiovasc Pharmacol. 1991 Sep;18(3):386-97. | |||
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