Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05VAN
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| Former ID |
DNC012807
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| Drug Name |
1-Ethyl-3-imidazol-1-ylmethyl-1H-indole
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| Synonyms |
CHEMBL115899; 72818-64-5; 1-Ethyl-3-imidazol-1-ylmethyl-1H-indole; SCHEMBL11496228; CTK2G2099; DTXSID10438234; BDBM50022117; ZINC27096766; 1-Ethyl-3-[(1H-imidazol-1-yl)methyl]-1H-indole; 1H-Indole, 1-ethyl-3-(1H-imidazol-1-ylmethyl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H15N3
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| Canonical SMILES |
CCN1C=C(C2=CC=CC=C21)CN3C=CN=C3
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| InChI |
1S/C14H15N3/c1-2-17-10-12(9-16-8-7-15-11-16)13-5-3-4-6-14(13)17/h3-8,10-11H,2,9H2,1H3
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| InChIKey |
KIIFZBAPVHIJQJ-UHFFFAOYSA-N
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| CAS Number |
CAS 72818-64-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Selective thromboxane synthetase inhibitors. 2. 3-(1H-imidazol-1-ylmethyl)-2-methyl-1H-indole-1-propanoic acid and analogues. J Med Chem. 1986 Mar;29(3):342-6. | |||
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