Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05TXS
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| Former ID |
DIB012458
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| Drug Name |
BMN-168
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| Synonyms |
Sapropterin prodrug, BioMarin; 6R-BH4 prodrug, BioMarin
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| Indication | Phenylketonuria [ICD-11: 5C50.0; ICD-10: E70, E70.1] | Investigative | [1] | |
| Company |
BioMarin Pharmaceutical Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phenylalanine hydroxylase (PAH) | Target Info | Modulator | [1] |
| BioCyc | Phenylalanine degradation/tyrosine biosynthesis | |||
| KEGG Pathway | Phenylalanine metabolism | |||
| Phenylalanine, tyrosine and tryptophan biosynthesis | ||||
| Metabolic pathways | ||||
| Biosynthesis of amino acids | ||||
| Pathwhiz Pathway | Phenylalanine and Tyrosine Metabolism | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Biogenic Amine Synthesis | ||||
| Metabolism of amino acids and derivatives | ||||
| Abnormal metabolism in phenylketonuria | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1240). | |||
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