Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05SOU
|
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| Former ID |
DIB018804
|
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| Drug Name |
all-trans-retinal
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
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| Formula |
C20H28O
|
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| Canonical SMILES |
CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=O)C)C
|
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| InChI |
1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
|
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| InChIKey |
NCYCYZXNIZJOKI-OVSJKPMPSA-N
|
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| CAS Number |
CAS 116-31-4
|
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3136, 3666, 83356, 228445, 416401, 416402, 493006, 589152, 3157260, 8143959, 8704598, 10504630, 10524847, 12276012, 14775466, 17388687, 24702066, 24899355, 24899382, 43760279, 48424039, 48425697, 49854777, 53790090, 53812631, 57407725, 77047160, 91615887, 103282386, 103847254, 113528124, 113584862, 117624017, 117682346, 124890043, 124890044, 124890045, 124890046, 124890047, 126523991, 126637303, 134975373, 135651434, 137004766, 137005733, 142478968, 144208203, 162219414, 164806111, 175265990
|
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| ChEBI ID |
CHEBI:17898
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cyclic nucleotide-gated channel alpha-2 (CNGA2) | Target Info | Inhibitor (gating inhibitor) | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2350). | |||
| REF 2 | All-trans-retinal shuts down rod cyclic nucleotide-gated ion channels: a novel role for photoreceptor retinoids in the response to bright light Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8372-7. | |||
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