Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D05SKE
|
|||
Former ID |
DNC006460
|
|||
Drug Name |
6-bromo-3-(pyridin-4-yl)-1H-indole
|
|||
Synonyms |
CHEMBL206257; 6-bromo-3-(pyridin-4-yl)-1H-indole
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C13H9BrN2
|
|||
Canonical SMILES |
C1=CC2=C(C=C1Br)NC=C2C3=CC=NC=C3
|
|||
InChI |
1S/C13H9BrN2/c14-10-1-2-11-12(8-16-13(11)7-10)9-3-5-15-6-4-9/h1-8,16H
|
|||
InChIKey |
KLYDZCDPTMADJL-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) | Target Info | Inhibitor | [1] |
BioCyc | Purine nucleotides degradation | |||
Urate biosynthesis/inosine 5'-phosphate degradation | ||||
Guanosine nucleotides de novo biosynthesis | ||||
Superpathway of purine nucleotide salvage | ||||
Purine nucleotides de novo biosynthesis | ||||
Guanosine ribonucleotides de novo biosynthesis | ||||
KEGG Pathway | Purine metabolism | |||
Drug metabolism - other enzymes | ||||
Metabolic pathways | ||||
Panther Pathway | De novo purine biosynthesis | |||
Reactome | Purine ribonucleoside monophosphate biosynthesis |
References | Top | |||
---|---|---|---|---|
REF 1 | Low molecular weight indole fragments as IMPDH inhibitors. Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.