Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05RQB
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| Former ID |
DNC000238
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| Drug Name |
Aphidicolin
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| Synonyms |
bis(hydroxymethyl)-dimethyl-[ ]diol; AC1LA8KN; 8,11a-Methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, (3R,4R,9R,11bS)-
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C20H34O4
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| Canonical SMILES |
CC12CCC(C(C1CCC3C24CCC(C(C3)C4)(CO)O)(C)CO)O
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| InChI |
1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1
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| InChIKey |
NOFOAYPPHIUXJR-APNQCZIXSA-N
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| CAS Number |
CAS 38966-21-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:2766
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Herpes simplex virus DNA polymerase UL30 (HSV UL30) | Target Info | Inhibitor | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Proteasome regulation of ULBP1 transcription. J Immunol. 2009 May 15;182(10):6600-9. | |||
| REF 2 | Characterization of an aphidicolin-resistant mutant of herpes simplex virus type 2 which induces an altered viral DNA polymerase. Virology. 1984 May;135(1):87-96. | |||
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