Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05QNO
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| Former ID |
DAP000378
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| Drug Name |
Decamethonium
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| Synonyms |
Decamethonum; Syncurine; DECAMETHONIUM ION; AIDS351484; AIDS-351484; Decamethylenebis(trimethylammonium)bromide; Syncurine (TN); Syncurine (*dibromide salt*); Trimethyl-[10-(trimethylazaniumyl)decyl]azanium; C 10 (VAN) (*dibromide salt*); N,N,N,N',N',N'-hexamethyldecane-1,10-diaminium; (DM)Br2; 1,10-Decanediaminium, N,N,N,N',N',N'-hexamethyl-(9CI); 1,10-Decanediaminium, N,N,N,N',N',N'-hexamethyl-, dibromide
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| Drug Type |
Small molecular drug
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| Indication | Muscle spasm [ICD-11: MB47.3] | Approved | [1] | |
| Therapeutic Class |
Neuromuscular Depolarizing Agents
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| Structure |
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Download2D MOL |
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| Formula |
C16H38N2+2
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| Canonical SMILES |
C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
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| InChI |
1S/C16H38N2/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6/h7-16H2,1-6H3/q+2
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| InChIKey |
MTCUAOILFDZKCO-UHFFFAOYSA-N
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| CAS Number |
CAS 156-74-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
13898, 794469, 826444, 5185327, 6088329, 7887087, 7979031, 8151891, 11111046, 11111047, 11466996, 11468116, 11486632, 12075375, 14872293, 22390067, 26697291, 26702368, 26756594, 29222118, 46476111, 46507737, 47440438, 47440439, 47662485, 48035316, 48110631, 49699002, 49867253, 50100213, 50104027, 50870859, 57321535, 85209970, 90341654, 92093426, 92308694, 103061021, 103352720, 103834884, 103956277, 104037963, 104302141, 111677851, 117392684, 124749671, 124879843, 124879844, 124879845, 124879846
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| ChEBI ID |
CHEBI:41934
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuronal acetylcholine receptor alpha-1 (CHRNA1) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 006931. | |||
| REF 2 | Potency of nondepolarizing muscle relaxants on muscle-type acetylcholine receptors in denervated mouse skeletal muscle.Acta Pharmacol Sin.2010 Dec;31(12):1541-6. | |||
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