Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05QIU
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| Former ID |
DIB016424
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| Drug Name |
Embeconazole
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| Synonyms |
CS-758; R-120758; Triazole derivative (oral, fungal infection), Daiichi Sankyo
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| Drug Type |
Small molecular drug
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| Indication | Fungal infection [ICD-11: 1F29-1F2F; ICD-10: B35-B49; ICD-9: 110-118] | Phase 1 | [1] | |
| Company |
Sankyo Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C27H25F3N4O3S
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| Canonical SMILES |
CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)SC3COC(OC3)C=CC=CC4=C(C=C(C=C4)C#N)F
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| InChI |
1S/C27H25F3N4O3S/c1-18(27(35,15-34-17-32-16-33-34)23-9-8-21(28)11-25(23)30)38-22-13-36-26(37-14-22)5-3-2-4-20-7-6-19(12-31)10-24(20)29/h2-11,16-18,22,26,35H,13-15H2,1H3/b4-2+,5-3+/t18-,22?,26?,27-/m1/s1
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| InChIKey |
XSRKBFUVSRRJDX-ILLAMVBCSA-N
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| CAS Number |
CAS 329744-44-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Candida Cytochrome P450 51 (Candi ERG11) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014655) | |||
| REF 2 | CS-758. Antifungal lanosterol 14alpha-demethylase inhibitor, 003, vol28, no3, 217-223. | |||
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