Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05QDC
|
|||
| Former ID |
DAP000743
|
|||
| Drug Name |
Acitretin
|
|||
| Synonyms |
Acitretina; Acitretine; Acitretinum; Etretin; Isoacitretin; Isoetretin; Neotigason; Soriatane; TMMP; Acitretina [Spanish]; Acitretine [French]; Acitretinum [Latin]; Retinoid etretin; U0279; Ro 10-1670; Ro 13-7652; Soriatane (TN); Soriatane, Acitretin; Acitretin (USAN/INN); Acitretin [USAN:INN:BAN]; All-trans-Acitretin; Ro 10-1670/000; Ro-10-1670; Ro-13-7652; Ro-10-1670/000; All-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid; (2E,4E,6E,8E)-3,7-dimethyl-9-[2,3,6-trimethyl-4-(methyloxy)phenyl]nona-2,4,6,8-tetraenoic acid; (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid; (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid; 13-cis-Acitretin; 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid; 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Psoriasis vulgaris [ICD-11: EA90; ICD-9: 696] | Approved | [1], [2] | |
| Therapeutic Class |
Keratolytic Agents
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H26O3
|
|||
| Canonical SMILES |
CC1=CC(=C(C(=C1C=CC(=CC=CC(=CC(=O)O)C)C)C)C)OC
|
|||
| InChI |
1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
|
|||
| InChIKey |
IHUNBGSDBOWDMA-AQFIFDHZSA-N
|
|||
| CAS Number |
CAS 55079-83-9
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
11039319, 12013101, 14899611, 17396912, 24868318, 26756475, 29216416, 39317834, 46509178, 47290859, 48415513, 49640651, 49836682, 49997927, 53786746, 57359098, 57650239, 78587872, 81092779, 91688963, 92714213, 93166775, 99437117, 103321496, 104170221, 113863074, 117544791, 118048888, 118312010, 121362527, 124757195, 124800949, 124892397, 125163999, 126624326, 126655575, 126665847, 131318569, 135004335, 135090960, 135610284, 135692120, 136368133, 137051948, 137058304, 140274245, 144115537, 144205565, 152029410, 152255026
|
|||
| ChEBI ID |
CHEBI:50173
|
|||
| ADReCS Drug ID | BADD_D00036 | |||
| SuperDrug ATC ID |
D05BB02
|
|||
| SuperDrug CAS ID |
cas=055079839
|
|||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7598). | |||
| REF 2 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 3 | Effects of acitretin on the expression of signaling pathway-related genes in epidermal squamous-cell carcinoma cells. Zhonghua Zhong Liu Za Zhi. 2006 Jan;28(1):21-4. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.