Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05QAD
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| Former ID |
DIB020832
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| Drug Name |
RO320-2947/001
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| Synonyms |
RO320-2947/001; GTPL791; SCHEMBL1223391
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C26H36ClN3O5
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| Canonical SMILES |
CC(C(CN1CCC(CC1)CC2=CC=C(C=C2)Cl)NC(=O)NC3=CC(=C(C(=C3)OC)OC)OC)O
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| InChI |
1S/C26H36ClN3O5/c1-17(31)22(16-30-11-9-19(10-12-30)13-18-5-7-20(27)8-6-18)29-26(32)28-21-14-23(33-2)25(35-4)24(15-21)34-3/h5-8,14-15,17,19,22,31H,9-13,16H2,1-4H3,(H2,28,29,32)/t17?,22-/m0/s1
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| InChIKey |
JYDVJNOBDUOZJC-UGNFMNBCSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | CCR3 messenger RNA (CCR3 mRNA) | Target Info | Antagonist | [2] |
| NetPath Pathway | IL3 Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 791). | |||
| REF 2 | Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists. Am J Respir Crit Care Med. 2002 Jun 15;165(12):1602-9. | |||
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