Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05QAA
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| Former ID |
DIB012934
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| Drug Name |
PNU-248686A
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| Synonyms |
3-(4'-Chlorobiphenyl-4-ylsulfonyl)-2(R)-hydroxy-2-(phenylsulfanylmethyl)propionic acid sodium salt
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C22H19ClNaO5S2
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| Canonical SMILES |
C1=CC=C(C=C1)SCC(CS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)Cl)(C(=O)O)O.[Na]
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| InChI |
1S/C22H19ClO5S2.Na/c23-18-10-6-16(7-11-18)17-8-12-20(13-9-17)30(27,28)15-22(26,21(24)25)14-29-19-4-2-1-3-5-19;/h1-13,26H,14-15H2,(H,24,25);/t22-;/m1./s1
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| InChIKey |
YQPKCDPUTCALSX-VZYDHVRKSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Matrix metalloproteinase (MMP) | Target Info | Modulator | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Determination of PNU-248686A, a novel matrix metalloproteinase inhibitor, in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format. J Chromatogr A. 2003 Feb 14;987(1-2):249-56. | |||
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