Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05PHX
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| Former ID |
DIB020951
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| Drug Name |
SKA-121
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| Synonyms |
SKA121; SKA 121
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C12H10N2O
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| Canonical SMILES |
CC1=CC2=C(C3=CC=CC=C13)OC(=N2)N
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| InChI |
1S/C12H10N2O/c1-7-6-10-11(15-12(13)14-10)9-5-3-2-4-8(7)9/h2-6H,1H3,(H2,13,14)
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| InChIKey |
JEGUERWMMMQFJV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium-activated potassium channel KCa3.1 (KCNN4) | Target Info | Activator | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1. Mol Pharmacol. 2014 Sep;86(3):342-57. | |||
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