Drug Information
Drug General Information | Top | |||
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Drug ID |
D05OML
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Former ID |
DNC014398
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Drug Name |
5-(3-hydroxyphenyl)-1,3,4-oxadiazole-2(3H)-thione
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Synonyms |
3-(5-Mercapto-[1,3,4]oxadiazol-2-yl)-phenol; 3-(5-mercapto-1,3,4-oxadiazol-2-yl)phenol; 299465-12-6; 3-(5-sulfanyl-1,3,4-oxadiazol-2-yl)phenol; CHEMBL595356; 3-(5-Mercapto-1,3,4-Oxadiazol-2-Yl)-Phenol; AO-365/08835025; 5-(3-hydroxyphenyl)-1,3,4-oxadiazole-2(3H)-thione; 5-[3-Hydroxyphenyl]-1,3,4-oxadiazole-2(3H)-thione; NSC524085; AC1LF1GV; Oprea1_836042; CTK8F4715; CTK8A0072; MolPort-000-932-334; ZX-AN016552; ZINC1605604; BB_SC-06098; CCG-15357; STK506749; FCH842308; BDBM50320729; BBL000571; AKOS000564154; FCH2245445; NSC-524085
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C8H6N2O2S
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Canonical SMILES |
C1=CC(=CC(=C1)O)C2=NNC(=S)O2
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InChI |
1S/C8H6N2O2S/c11-6-3-1-2-5(4-6)7-9-10-8(13)12-7/h1-4,11H,(H,10,13)
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InChIKey |
CNOGHDSTUCQSOV-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
BioCyc | (S)-reticuline biosynthesis | |||
Eumelanin biosynthesis | ||||
L-dopachrome biosynthesis | ||||
KEGG Pathway | Tyrosine metabolism | |||
Riboflavin metabolism | ||||
Metabolic pathways | ||||
Melanogenesis | ||||
Pathwhiz Pathway | Riboflavin Metabolism | |||
Tyrosine Metabolism | ||||
WikiPathways | Dopamine metabolism |
References | Top | |||
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REF 1 | New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triaz... Bioorg Med Chem. 2010 Jun 1;18(11):4042-8. |
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