Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05NRG
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| Drug Name |
Isoflavone derivative 8
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| Synonyms |
PMID26666870-Compound-26
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| Drug Type |
Small molecular drug
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| Company |
UNIVERSITA' DEGLI STUDI DI SIENA,UNIVERSITA' DEGLI STUDI DI ROMA "LA SAPIENZA"
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Smoothened homolog (SMO) | Target Info | Inhibitor | [1] |
| Zinc finger protein GLI1 (Gli1) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Smoothened homolog (SMO) | Target's Patent Info | [1] | |
| Zinc finger protein GLI1 (Gli1) | Target's Patent Info | [1] | ||
| KEGG Pathway | Hedgehog signaling pathway | |||
| Pathways in cancer | ||||
| Proteoglycans in cancer | ||||
| Basal cell carcinoma | ||||
| Panther Pathway | Hedgehog signaling pathway | |||
| Pathway Interaction Database | Signaling events mediated by the Hedgehog family | |||
| Hedgehog signaling events mediated by Gli proteins | ||||
| Reactome | Class B/2 (Secretin family receptors) | |||
| Hedgehog 'off' state | ||||
| Activation of SMO | ||||
| WikiPathways | Hedgehog Signaling Pathway | |||
| Hair Follicle Development: Organogenesis (Part 2 of 3) | ||||
| Hair Follicle Development: Induction (Part 1 of 3) | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| GPCR ligand binding | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Evaluation of WO2014207069 A1: Multitarget Hedgehog pathway inhibitors and uses thereof.Expert Opin Ther Pat. 2016;26(4):529-35. | |||
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