Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05MVA
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| Former ID |
DIB012776
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| Drug Name |
RGD-891
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| Synonyms |
Klerval; RPR-109039; N-Ethyl-N-[4-(4-piperidyl)butyryl]-glycyl-L-aspartyl-L-(3-cyclohexyl)alaninamide
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| Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Phase 1 | [1] | |
| Angina pectoris [ICD-11: BA40; ICD-9: 413] | Discontinued in Phase 2 | [2] | ||
| Structure |
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Download2D MOL
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| Formula |
C26H45N5O6
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| Canonical SMILES |
CCN(CC(=O)NC(CC(=O)O)C(=O)NC(CC1CCCCC1)C(=O)N)C(=O)CCCC2CCNCC2
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| InChI |
1S/C26H45N5O6/c1-2-31(23(33)10-6-9-18-11-13-28-14-12-18)17-22(32)29-21(16-24(34)35)26(37)30-20(25(27)36)15-19-7-4-3-5-8-19/h18-21,28H,2-17H2,1H3,(H2,27,36)(H,29,32)(H,30,37)(H,34,35)/t20-,21-/m0/s1
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| InChIKey |
PWINFPFVCZSLBF-SFTDATJTSA-N
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| CAS Number |
CAS 169512-56-5
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pharmacokinetics, pharmacodynamics, and safety of a platelet GPIIb/IIIa antagonist, RGD891, following intravenous administration in healthy male volunteers. J Clin Pharmacol. 2000 Nov;40(11):1245-56. | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007824) | |||
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