Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05KFH
|
|||
| Drug Name |
CD171 specific CAR T cells expressing EGFRt
|
|||
| Drug Type |
CAR T Cell Therapy
|
|||
| Indication | Ganglioneuroblastoma [ICD-11: 2A00.11; ICD-10: C69-C72, C71] | Phase 1 | [1] | |
| Neuroblastoma [ICD-11: 2D11.2] | Phase 1 | [1] | ||
| Company |
Seattle Children's Hospital
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neural cell adhesion molecule L1 (L1CAM) | Target Info | CAR-T-Cell-Therapy | [1] |
| KEGG Pathway | Axon guidance | |||
| Cell adhesion molecules (CAMs) | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02311621) Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01 | |||
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