Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05JJL
|
|||
| Former ID |
DIB019885
|
|||
| Drug Name |
furin inhibitor peptide
|
|||
| Synonyms |
CHEMBL502642; furin inhibitor peptide; GTPL8668
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C58H113N29O13
|
|||
| Canonical SMILES |
CC(C(C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)O)C(=O)N)N)O
|
|||
| InChI |
1S/C58H113N29O13/c1-30(78-45(92)35(16-8-24-73-54(63)64)85-52(99)40-21-13-29-87(40)53(100)41(61)31(2)88)44(91)79-36(17-9-25-74-55(65)66)48(95)82-38(19-11-27-76-57(69)70)50(97)83-37(18-10-26-75-56(67)68)49(96)81-33(14-4-6-22-59)46(93)80-34(15-5-7-23-60)47(94)84-39(20-12-28-77-58(71)72)51(98)86-42(32(3)89)43(62)90/h30-42,88-89H,4-29,59-61H2,1-3H3,(H2,62,90)(H,78,92)(H,79,91)(H,80,93)(H,81,96)(H,82,95)(H,83,97)(H,84,94)(H,85,99)(H,86,98)(H4,63,64,73)(H4,65,66,74)(H4,67,68,75)(H4,69,70,76)(H4,71,72,77)/t30-,31+,32+,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m0/s1
|
|||
| InChIKey |
XIHRZTWKTVFWSV-HQSWAJDZSA-N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dibasic-processing enzyme (Furin) | Target Info | Inhibitor | [1] |
| Proprotein convertase subtilisin/kexin type 4 (PCSK4) | Target Info | Inhibitor | [1] | |
| Proprotein convertase subtilisin/kexin type 5 (PCSK5) | Target Info | Inhibitor | [1] | |
| Proprotein convertase subtilisin/kexin type 6 (PCSK6) | Target Info | Inhibitor | [1] | |
| Proprotein convertase subtilisin/kexin type 7 (PCSK7) | Target Info | Inhibitor | [1] | |
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | Alzheimer disease-amyloid secretase pathway | |||
| Alzheimer disease-presenilin pathway | ||||
| Endothelin signaling pathway | ||||
| Pathway Interaction Database | Notch signaling pathway | |||
| p75(NTR)-mediated signaling | ||||
| HIF-1-alpha transcription factor network | ||||
| Glypican 3 network | ||||
| WikiPathways | Signalling by NGF | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens. J Biol Chem. 2007 Jul 20;282(29):20847-53. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.